Hematopoiesis in pantothenic acid-deficient rats.
نویسندگان
چکیده
منابع مشابه
Carbohydrate metabolism and adrenal cortical function in the pantothenic acid-deficient rat.
A relationship between pantothenic acid and the adrenal gland has been evident since the earliest work with this vitamin was done. Morgan and Simms (1) found pathologic changes in the adrenals of rats on diets free from “filtrate factor,” and reported (2) that the achromotrichia of rats maintained on these diets could be at least partly reversed by extracts of the thyroid and of the adrenal cor...
متن کاملTissue coenzyme A in normal and induced states of growth.
Results of studies on pantothenic acid-deficient rats stimulated with anterior pituitary growth hormone (l-3) suggest involvement of pantothenic acid, or its metabolically active form, coenzyme A (4), in the mechanism by which growth hormone stimulates the growth process. Lotspeich (l), for example, describes the rapid production of symptoms of acute pantothenic acid deficiency as a sequel to t...
متن کاملThe modification of choline deficiency by simultaneous pantothenic acid deficiency.
It was found recently (1) that feeding a cholesterol-rich diet to pantothenic acid-deficient rats did not result in the fatty livers and high levels of cholesterol in liver and serum seen in comparable animals maintained on a normal diet. Decrease in food intake appeared not to account for this phenomenon, since the food intake of the deficient group on a body weight basis was higher than that ...
متن کاملThe metabolism in vitro of cardiac muscle in pantothenic acid deficiency.
An important r81e for pantothenic acid in carbohydrate metabolism was suggested by studies in which pantothenic acid-deficient bacteria (1, 2) and liver (3) were observed to utilize pyruvate at rates much less than normal. The subsequent discovery of Lipmann and his colleagues that the coenzyme of acetylation (coenzyme A) (4) contained pantothenic acid (5) provided a stimulus for the reinvestig...
متن کاملFURTHER OBSERVATIONS ON T H E PRODUCTION AND PREVENTION OF DIETARY HEPATIC INJURY IN RATS* BY PAUL GYORGY, M.D., AlUm
I t was first reported in 1939 (1) that hepatic injury, mainly in the form of acute zonal or diffuse necrosis, occurred irregularly in young rats fed a basal diet devoid of vitamin B (casein 18, cane sugar 68, melted butter fat 8, cod liver oil 2, salt mixture 4) and supplemented with thiamine, riboflavin, and pyridoxine. Thus, this ration was still deficient in several other members of the vit...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Blood
دوره 2 5 شماره
صفحات -
تاریخ انتشار 1947